Vitamin D and Type 1 Diabetes Mellitus

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Immune Function of Vitamin D in Type 1 Diabetes Mellitus

Vitamin D is a well-known fat-soluble vitamin which is essential in the homeostasis of calcium and phosphorus. Vitamin D deficiency causes skeletal disorders, including rickets, osteomalacia, and osteoporosis. However, recent studies revealing the immunomodulatory effects of vitamin D have opened up a new understanding and possibility in this field. It has been proved that vitamin D is related ...

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Effect of Vitamin D Supplementation on Pancreatic Β -Cell Function in Patients with Type 1 Diabetes Mellitus and Vitamin D Deficiency: A Clinical Trial Study

Background Considering the increasing prevalence of type 1 diabetes mellitus (T1DM) as an autoimmune disease in recent years and the positive effects of vitamin D (VD) on this disease, especially the preventive effect of VD on progressive reduction of pancreatic β-cells, we aimed to investigate the effect of VD on pancreatic β-cell function in T1DM patients. Materials and Methods From Sep 2016 ...

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Vitamin D and diabetes mellitus.

The vitamin D endocrine system in now recognized as subserving a wide range of fundamental biological functions in cell differentiation, inhibition of cell growth as well as immunomodulation. Both forms of immunity, namely adaptive and innate, are regulated by 1,25(OH)2D3. The immune-modulatory properties of vitamin D suggest that it could play a potential therapeutic role in prevention of type...

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ژورنال

عنوان ژورنال: INTERNATIONAL JOURNAL OF ENDOCRINOLOGY

سال: 2016

ISSN: 2307-1427,2224-0721

DOI: 10.22141/2224-0721.3.75.2016.76646